CIA-5358-The cognitive impact of anticholinergics: A clinic
نویسندگان
چکیده
1Regenstrief Institute, Inc. Indianapolis, In, UsA; 2Indiana University Center for Aging Research; 3Department of Medicine, Indiana University school of Medicine, Indianapolis, In, UsA; 4Wishard health services, Indianapolis, In, UsA; 5school of Pharmacy and Pharmaceutical sciences, Purdue University, West Lafayette, In, UsA; 6Kent Institute of Medicine and health sciences, University of Kent, Canterbury, Kent, UK; 7Kent and Medway nhs Trust, Dartford, Kent, UK; 8Postgraduate Medical Institute, University of hull, hull, UK; 9Penn state University school of nursing; 10Department of Psychiatry, Penn state College of Medicine; 11Indiana University Medical group – Primary Care, Indianapolis, In, UsA
منابع مشابه
Use of anticholinergics and the risk of cognitive impairment in an African American population.
BACKGROUND Anticholinergic properties of certain medications often go unrecognized, and are frequently used by the elderly population. Few studies have yet defined the long-term impact of these medications on the incidence of cognitive impairment. METHODS We report a 6-year longitudinal, observational study, evaluating 1,652 community-dwelling African American subjects over the age of 70 year...
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Anticholinergics, and drugs with anticholinergic properties, are widely and frequently prescribed, especially to the elderly. It is well known that these drugs decrease cognitive function and increase the risk of dementia. Although the mechanism of anticholinergic drug-induced cognitive impairment has been assumed to be functionally reduced acetylcholine (ACh) neurotransmission, some data have ...
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متن کاملAnticholinergic medication use and cognitive impairment in the older population: the medical research council cognitive function and ageing study.
OBJECTIVES To determine whether the use of medications with possible and definite anticholinergic activity increases the risk of cognitive impairment and mortality in older people and whether risk is cumulative. DESIGN A 2-year longitudinal study of participants enrolled in the Medical Research Council Cognitive Function and Ageing Study between 1991 and 1993. SETTING Community-dwelling and...
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